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Biology

Explore how living things work, from molecules and cells to ecosystems.

46 activities in 7 units · 6 simulations, 21 practice activities, 19 labs

Measurement3

  • Fair Test Lab screenshot Lab

    Fair Test Lab

    Design fair tests at six science stations. Find hidden variables, collect repeated measurements, and explain your evidence.

    NGSS SEP 3, 4, 5; CCC Cause and Effect
    Launch Fair Test Lab
  • Graph Doctor screenshot Practice

    Graph Doctor

    Run the Graph Clinic: diagnose and fix sick lab-report graphs, then read them: values, slopes, trends and outliers. 10-question runs.

    Launch Graph Doctor
  • Read the Glassware screenshot Practice

    Read the Glassware

    Run the lab's measuring desk: read cylinders, burets, rulers, thermometers and balances to the right digit. 10-question runs.

    Launch Read the Glassware

Cells4

  • Build a Cell screenshot Simulation

    Build a Cell

    Click organelles onto a blank cell and discover which cell type you've built.

    Launch Build a Cell
  • Microscope Slide Lab screenshot Lab

    Microscope Slide Lab

    Prepare wet-mount slides and focus four real specimens with coarse and fine controls.

    Launch Microscope Slide Lab
  • Organelle Repair Shop screenshot Practice

    Organelle Repair Shop

    Fix sick cells: read the symptom, tap the broken organelle and swap in a working one. Plant, animal or bacterium? 10-question runs.

    NGSS HS-LS1-2
    Launch Organelle Repair Shop

Biomolecules3

  • Macromolecule Builder screenshot Lab

    Macromolecule Builder

    Build carbohydrates, lipids, proteins and DNA from real 3D monomers. Count the water at every bond, melt fats, unfold a protein.

    NGSS HS-LS1-6, HS-LS1-1, HS-PS1-3
    Launch Macromolecule Builder
  • Polymer Workshop screenshot Practice

    Polymer Workshop

    Run a molecular workshop: build macromolecules from monomers, break them down by hydrolysis, and count every water. 10-question runs.

    Launch Polymer Workshop

Enzymes & Energy8

  • Enzyme Exploration screenshot Simulation

    Enzyme Exploration

    Build an enzyme reaction, watch molecules collide, see denaturation, then take the test.

    Launch Enzyme Exploration
  • Liver Catalase Lab screenshot Lab

    Liver Catalase Lab

    Run a step-by-step catalase experiment with a control, then graph your data and argue from evidence.

    Launch Liver Catalase Lab
  • Bubble Lab: Elodea Photosynthesis screenshot Lab

    Bubble Lab: Elodea Photosynthesis

    Count the O₂ bubbles from an Elodea sprig as you change the lamp's distance and color, graph the rate, and zoom in to the chloroplast.

    NGSS HS-LS1-5, HS-LS2-5, MS-LS1-6
    Launch Bubble Lab: Elodea Photosynthesis
  • Leaf Disks & Yeast Balloons screenshot Lab

    Leaf Disks & Yeast Balloons

    Float leaf disks under a lamp for photosynthesis, inflate yeast balloons for respiration, then graph, find rates and write a CER.

    NGSS HS-LS1-5, HS-LS1-7, MS-LS1-6, MS-LS1-7
    Launch Leaf Disks & Yeast Balloons
  • Atom Accountant screenshot Practice

    Atom Accountant

    Audit the cell's Atom Bank: sort, balance and trace every C, H and O through photosynthesis and respiration. 10-question runs.

    Launch Atom Accountant
  • Enzyme Locksmith screenshot Practice

    Enzyme Locksmith

    Fit each substrate key to its enzyme's active site, then set temperature, pH and substrate so the reaction runs fast. 10-question runs.

    NGSS HS-LS1-6
    Launch Enzyme Locksmith
  • ATP Power Company screenshot Practice

    ATP Power Company

    Run a cell's power plant: choose aerobic respiration or fermentation, load glucose and deliver exactly the ATP each cell orders.

    NGSS HS-LS1-7
    Launch ATP Power Company

Homeostasis5

  • Homeostasis Lab screenshot Lab

    Homeostasis Lab

    Investigate a teen runner or a radish, graph your own data, and explain it with a negative or positive feedback loop.

    NGSS HS-LS1-3, HS-LS1-2
    Launch Homeostasis Lab
  • Osmosis Spa screenshot Practice

    Osmosis Spa

    Run a spa for cells: name each bath, predict lysis, crenation, turgor or plasmolysis, and mix baths to order. AP water potential too.

    NGSS HS-LS1-3
    Launch Osmosis Spa
  • Membrane Transport & Osmosis Lab screenshot Lab

    Membrane Transport & Osmosis Lab

    Zoom from a beaker to one protein. Watch diffusion, channels, carriers, aquaporins, pumps and vesicles carry molecules across a membrane.

    NGSS HS-LS1-3, HS-LS1-2, HS-PS1-3
    Launch Membrane Transport & Osmosis Lab
  • Membrane Bouncer screenshot Practice

    Membrane Bouncer

    Work the door of a cell: send each molecule through the bilayer, a channel or carrier, a pump, or a vesicle. 10-question runs.

    Launch Membrane Bouncer
  • Homeostasis ER screenshot Practice

    Homeostasis ER

    Be the ER doctor: rebuild each patient's feedback loop and watch their chart return to the set point. 10-question runs.

    Launch Homeostasis ER

Genetics14

  • DNA to Protein Exploration screenshot Simulation

    DNA to Protein Exploration

    Build DNA, copy it to mRNA, translate it, fold the protein, then mutate the gene. General Biology and AP levels.

    Launch DNA to Protein Exploration
  • Genetics Counseling Clinic screenshot Practice

    Genetics Counseling Clinic

    Study family histories and work the Punnett squares to answer couples' inheritance questions.

    Launch Genetics Counseling Clinic
  • Pedigree Lab screenshot Lab

    Pedigree Lab

    Explore inheritance patterns on family trees, build pedigrees from a written story, and test yourself at General or AP level.

    NGSS HS-LS3-1, HS-LS3-3
    Launch Pedigree Lab
  • Cell Cycle & Mitosis Lab screenshot Lab

    Cell Cycle & Mitosis Lab

    Watch living cells divide in time-lapse, from dish to chromosomes. Time each phase, switch off checkpoints and see how cancer starts.

    NGSS HS-LS1-4, HS-LS3-2, HS-LS1-3
    Launch Cell Cycle & Mitosis Lab
  • Biotechnology Lab screenshot Lab

    Biotechnology Lab

    Cut DNA with restriction enzymes, size the pieces on a gel, copy the insulin gene by PCR and splice it into a plasmid.

    NGSS HS-LS3-1, HS-LS1-1
    Launch Biotechnology Lab
  • Meiosis & Inheritance Lab screenshot Lab

    Meiosis & Inheritance Lab

    Follow real alleles through meiosis, then raise peas, corn and fruit flies and count their traits: Punnett squares, linkage, chi-square.

    NGSS HS-LS3-1, HS-LS3-2, HS-LS3-3, HS-LS1-4
    Launch Meiosis & Inheritance Lab
  • Ribosome Diner screenshot Practice

    Ribosome Diner

    Cook at the Ribosome Diner: transcribe DNA tickets into mRNA, read codons on the codon wheel and chain the amino acids. 10-question runs.

    NGSS HS-LS1-1
    Launch Ribosome Diner
  • Chromosome Choreographer screenshot Practice

    Chromosome Choreographer

    Set the cell stage for each phase of mitosis: place chromosomes, spindle and nuclear envelope, then count what's there. 10-question runs.

    Launch Chromosome Choreographer
  • Gamete Factory screenshot Practice

    Gamete Factory

    Run chromosomes through meiosis and ship every kind of egg or sperm a genotype can make. 10-question runs.

    Launch Gamete Factory
  • Creature Breeder screenshot Practice

    Creature Breeder

    Choose parents, build Punnett squares, predict trait odds and hatch random litters across Mendelian and non-Mendelian inheritance.

    NGSS HS-LS3-2, HS-LS3-3
    Launch Creature Breeder
  • Mutation Detective screenshot Practice

    Mutation Detective

    Work the night shift at a genetics crime lab: line up normal and mutant genes, find the change, classify it and predict the protein.

    NGSS HS-LS3-2
    Launch Mutation Detective
  • Gel Crime Lab screenshot Practice

    Gel Crime Lab

    Run the DNA bench at a forensic lab: cut samples with restriction enzymes, run a gel and compare every band with the evidence.

    NGSS HS-LS3-1
    Launch Gel Crime Lab
  • Probability Plinko screenshot Practice

    Probability Plinko

    Predict Mendelian odds, then drop 4, 40 and 400 offspring through a Plinko board of gamete gates and see how samples wobble.

    NGSS HS-LS3-3
    Launch Probability Plinko

Evolution & Ecology9

  • Food Web Architect screenshot Practice

    Food Web Architect

    Build real food webs, tag trophic roles, predict cascades, and trace shrinking energy through six living ecosystems.

    NGSS HS-LS2-4, HS-LS2-6
    Launch Food Web Architect
  • Cladogram Builder screenshot Practice

    Cladogram Builder

    Curate a museum's Tree of Life hall: build cladograms from trait tables and DNA data, tick shared derived traits, read who is related.

    NGSS HS-LS4-1
    Launch Cladogram Builder
  • Bone Matcher screenshot Practice

    Bone Matcher

    Run a museum's bone prep lab: tag matching bones in human, whale, bat, bird and horse limbs, then label homologous, analogous or vestigial.

    NGSS HS-LS4-1
    Launch Bone Matcher
  • Natural Selection Lab screenshot Lab

    Natural Selection Lab

    Predators hunt real prey in four real habitats. Change the environment and watch allele frequencies and population size shift.

    NGSS HS-LS4-2, HS-LS4-4, HS-LS3-3, HS-LS2-1, HS-LS4-1, HS-LS2-7
    Launch Natural Selection Lab
  • Evidence of Evolution Lab screenshot Lab

    Evidence of Evolution Lab

    Dig whale fossils from dated rock, compare forelimb bones, count protein differences, and build trees from bones and DNA.

    NGSS HS-LS4-1
    Launch Evidence of Evolution Lab
  • Ecosystem Dynamics Lab screenshot Lab

    Ecosystem Dynamics Lab

    Rabbits fill a meadow until the grass runs out, wolves and moose cycle on Isle Royale, and kelp falls to urchins when sea otters vanish.

    NGSS HS-LS2-1, HS-LS2-2, HS-LS2-4, HS-LS2-6
    Launch Ecosystem Dynamics Lab
  • Isopod Choice Chamber screenshot Lab

    Isopod Choice Chamber

    Set up a two-sided choice chamber and watch isopods pick their preferred environment.

    Launch Isopod Choice Chamber
  • Succession Explorer screenshot Simulation

    Succession Explorer

    Watch life return to new lava, glacial till and burned or logged forest, and see why soil decides primary vs. secondary succession.

    NGSS HS-LS2-6, HS-LS2-7, HS-LS4-6, MS-LS2-4
    Launch Succession Explorer
  • Geologic Time & Fossils Lab screenshot Lab

    Geologic Time & Fossils Lab

    Read a cliff’s history from its clues, date samples with radioactive clocks, and place fossil beds on the ICS time scale.

    45 minNGSS HS-ESS1-6; MS-ESS1-4; HS-LS4-1
    Launch Geologic Time & Fossils Lab